As most of us know, signs and symptoms of various illnesses intersect. Pancreatic cancer symptoms are no exception: while fatigue can be attributed to it, fatigue can also be attributed to other conditions such as depression. Cancer is a very difficult subject to deal with. Unfortunately, there is still no cure, but many people donate to cancer charities in hopes of offering their support. Ultimately, if you suspect that you or your loved one has pancreatic cancer, here are some early signs to watch out for:

1. Abdominal pain

If you find that you’re experiencing pain located in the back or upper abdomen, this could be an early sign of pancreatic cancer. However, if the pain already has a known cause—such as an alternative condition—then pancreatic cancer is less likely. If the abdominal pain is caused by pancreatic cancer, it will come and go in the early stages. Then, as the tumor grows and advances, so too will the pain—which is often more prevalent after you eat or lie down.

2. Jaundice

While it’s painless, if you have pancreatic cancer you may begin to notice yellowing of your eyes and skin. This occurs when the bile duct of the pancreas is blocked by the tumor. In addition to yellowing eyes and skin, jaundice is also responsible for greasy pale stools that float in the toilet, as well as dark urine. If you suspect that there might be a problem with your liver, keep an eye out for jaundice.

3. Unexplained weight loss

Although unexplained weight loss can be a symptom of many different conditions—both mental, such as depression, and physical, such as an overactive thyroid—it can also be an early sign of pancreatic cancer. Cancer cachexia can result in the body needing to burn more calories than what is typical, alongside decreasing your appetite and breaking down the protein of your muscles. No matter what, though, if you’re experiencing unexplained weight loss, it’s likely a good idea to talk to a medical professional to figure out the root cause.

4. Fatigue

Whether you have a preexisting health condition or you’ve stayed up all night long with the kids, there’s lots of reasons why you might feel fatigued. Pancreatic cancer is unfortunately one of them, however if you have fatigue on its own, separate from all—if not most—of the other early signs, then it’s probably reasonable to assume that the cause of this fatigue is not caused by pancreatic cancer. Still, if you’re concerned that something doesn’t feel right—pancreatic cancer or otherwise—speaking to a medical professional might help get to the bottom of it.

5. Problems with digestion

Once again, a tumor blocking the bile duct in the pancreas can result in greasy pale stools or dark urine. Nausea and indigestion, too, can be linked to pancreatic cancer. Diarrhea—resulting from a tumor or pancreatic cyst on the small intestine or stomach, which in turn causes a digestive tract blockage—is another sign of pancreatic cancer. It’s advised that, if you have diarrhea for over seven days with no explainable reason, you should call your GP or NHS 111.